Personalized AAV programs that turn biology into precision medicine
Axnmihn specializes in adeno-associated virus (AAV) gene therapy and offers personalized methods for genetic diseases through laboratory services — vector design, assay development, and preclinical support.
AAV engineering
Vancouver, BC
Custom lab services
Platform snapshot
- • Disease-sensing RNA/protein modules
- • AND/OR/NOT logic to enhance safety
- • Effectors tuned per indication
- • AAV (and LNP) delivery options
Technology — how it works
A modular toolkit combining sensing, logic, and effectors inside an optimized delivery system.
Detect transcripts/proteins that define disease states.
AND/OR/NOT circuits minimize off‑target activity.
Control expression, immune tuning, or apoptosis.
AAV serotypes mapped to tissue biodistribution.
Services — from concept to data
Capsid selection, promoters, codon optimization, and payload engineering oriented to target tissue.
Potency assays, qPCR/NGS, biodistribution, and stability testing to support program decisions.
Patient‑specific strategy and lab workflows with secure, compliant handling.
- • Design dossier with rationale and predicted tropism
- • Assay plan, protocols, and datasets
- • Non‑confidential report for collaborators
Pipeline — example programs
| Code | Indication | Modality | Status | Next milestone |
|---|---|---|---|---|
| AX‑101 | Solid tumor immuno‑circuit | AAV, AND gate | Lead optimization | Vector package finalize |
| AX‑202 | Fibrosis‑sensing therapy | AAV, NOT gate | In vivo PoC | Biodistribution readout |
| AX‑303 | Autoimmune tolerance | Ex vivo, OR gate | Target discovery | Hit validation |
About Axnmihn
Translate programmable biology into patient‑specific treatments for rare and complex genetic disease.
LeadershipAris Eznmihn — Chief Executive Officer
Based in Vancouver, BC (address below). We collaborate with academic and industry partners.
Work with usAdvisors, collaborators, and early hires are welcome. Reach out with a short note.
Resources
Overview of our AAV approach. (Coming soon)
Synthetic data showing assay outputs. (Coming soon)
Logo files and brand guide. (Coming soon)